Migraine

 Migraine is a relatively common disorder. Approximately 17.6% of women and 6% of men suffer migraine. According to the research conducted among the population, women who suffer migraines Caucasian origin (20.4%) is significantly higher than African American women (16.2%) and Asian (9.2%), which reliably points to a genetic predisposition to develop the disease. The incidence of migraine falls on the most productive years of life, ranging from 25 to 55 years. 90% of those suffering from migraine, carry their first attack before his fortieth birthday. Assessing the quality of life for people who suffer migraines, lower than that of patients with other chronic illnesses such as arterial hypertension, diabetes, heart disease, because these people live in constant fear of attack, which violates their fitness, ability to take care of their loved ones.
It has been proved that the prevalence of migraines is family. Genetic effects are especially pronounced in migraine with aura. If both parents had a migraine attack somewhere in their lives, the probability of that happenings to their children is 60 - 90%. If migraine attacks were evident in a mother, the risk of the disease is 72% when the father is 30%. Men who suffer migraines, have mothers who fell ill with the disease four times more often than fathers.
 
Several studies have demonstrated involvement in the pathogenesis of migraine genes that determine the metabolism mono amines, particularly serotonin.
 
It is now believed that migraines are involved in the pathogenesis of many genes as well as its clinical manifestations are important environmental factors and psychological factors.
 
Migraine is a chronic disorder with episodic worsening. It can be with stereotypical feelings arising directly to the sore attack: twinkle to the eyes, the outbreak of light, distorted perception of the world, limb numbness, a feeling in the stomach, etc. But often the pain episode begins suddenly, without warning or aura. Sometimes after aura headache is developing, such attacks are "grace migraine".